[HTML][HTML] Chemotherapy and transplantation: the role of immunosuppression in malignancy and a review of antineoplastic agents in solid organ transplant recipients
JC Krisl, VP Doan - American Journal of Transplantation, 2017 - Elsevier
It is estimated that solid organ transplant recipients have a two-to fourfold greater overall risk
of malignancy than the general population. Some of the most common malignancies after
transplant include skin cancers and posttransplant lymphoproliferative disorder. In addition
to known risk factors such as environmental exposures, genetics, and infection with
oncogenic viruses, immunosuppression plays a large role in the development of cancer
through the loss of the immunosurveillance process. The purpose of this article is to explain …
of malignancy than the general population. Some of the most common malignancies after
transplant include skin cancers and posttransplant lymphoproliferative disorder. In addition
to known risk factors such as environmental exposures, genetics, and infection with
oncogenic viruses, immunosuppression plays a large role in the development of cancer
through the loss of the immunosurveillance process. The purpose of this article is to explain …