Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers
AA Diaz, L Zhou, TP Young, ML McDonald… - Academic radiology, 2014 - Elsevier
Rationale and Objectives Computed tomography (CT) of the chest can be used to assess
pectoralis muscle area (PMA) and subcutaneous adipose tissue (SAT) area. Adipose tissue
content is associated with inflammatory mediators in chronic obstructive pulmonary disease
(COPD) subjects. Based on gender differences in body composition, we aimed to assess the
hypothesis that in subjects with COPD, the relationships between PMA, SAT, and blood
biomarkers of inflammation differ by gender. Materials and Methods We compared chest CT …
pectoralis muscle area (PMA) and subcutaneous adipose tissue (SAT) area. Adipose tissue
content is associated with inflammatory mediators in chronic obstructive pulmonary disease
(COPD) subjects. Based on gender differences in body composition, we aimed to assess the
hypothesis that in subjects with COPD, the relationships between PMA, SAT, and blood
biomarkers of inflammation differ by gender. Materials and Methods We compared chest CT …