[HTML][HTML] Serum levels of interleukin-1 beta associate better with severity of simple steatosis than liver function tests in morbidly obese patients

LF Palomera, AY Gómez-Arauz… - Journal of Research …, 2018 - journals.lww.com
Background: In high-fat diet-fed mice, interleukin-1 beta (IL-1 beta) has been shown to play
a key role in hepatic steatosis. However, it remains unknown whether IL-1 beta could be
associated with different grades of steatosis in obese humans. Materials and Methods:
Morbidly obese patients (n= 124) aged 18–65 years were divided into four groups: no
steatosis (controls), mild steatosis, moderate steatosis, and severe steatosis using
abdominal ultrasound. IL-1 beta serum levels and liver function tests were measured and …