Is there still a role for digoxin in the management of atrial fibrillation?
JB Washam, MR Patel - Current Cardiology Reports, 2018 - Springer
JB Washam, MR Patel
Current Cardiology Reports, 2018•SpringerPurpose of Review A number of recent observational analyses have assessed clinical
outcomes associated with digoxin use in patients with atrial fibrillation. In this review, we
review these data and provide suggestions on the contemporary use of digoxin in patients
with atrial fibrillation as supported by the recent evidence. Recent Findings Observational
data from clinical trials and registries have provided variable results on the safety and
efficacy of chronic digoxin use in patients with atrial fibrillation. In general, results have been …
outcomes associated with digoxin use in patients with atrial fibrillation. In this review, we
review these data and provide suggestions on the contemporary use of digoxin in patients
with atrial fibrillation as supported by the recent evidence. Recent Findings Observational
data from clinical trials and registries have provided variable results on the safety and
efficacy of chronic digoxin use in patients with atrial fibrillation. In general, results have been …
Purpose of Review
A number of recent observational analyses have assessed clinical outcomes associated with digoxin use in patients with atrial fibrillation. In this review, we review these data and provide suggestions on the contemporary use of digoxin in patients with atrial fibrillation as supported by the recent evidence.
Recent Findings
Observational data from clinical trials and registries have provided variable results on the safety and efficacy of chronic digoxin use in patients with atrial fibrillation. In general, results have been consistent with an associated increase in adverse clinical outcomes with digoxin use in atrial fibrillation patients without heart failure. In atrial fibrillation patients with heart failure, while the weight of evidence suggested an associated risk with digoxin therapy, the results are inconsistent.
Summary
In patients with atrial fibrillation without heart failure, digoxin should generally be avoided. In atrial fibrillation patients with heart failure, digoxin should generally be reserved for patients that do not achieve adequate rate control or are not tolerant of other rate control therapies.
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