[HTML][HTML] Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver

AE Reszko, T Kasumov, BA Pierce, F David… - Journal of Biological …, 2003 - ASBMB
While a number of studies underline the importance of anaplerotic pathways for hepatic
biosynthetic functions and cardiac contractile activity, much remains to be learned about the
sites and regulation of anaplerosis in these tissues. As part of a study on the regulation of
anaplerosis from propionyl-CoA precursors in rat livers and hearts, we investigated the
degree of reversibility of the reactions of the propionyl-CoA pathway. Label was introduced
into the pathway via NaH 13 CO 3,[U-13 C 3] propionate, or [U-13 C 3] lactate+[U-13 C 3] …