Animal models in type 2 diabetes research: an overview

K Srinivasan, P Ramarao - Indian journal of medical research, 2007 - journals.lww.com
Type 2 diabetes is a complex and heterogeneous disorder presently affecting more than 100
million people worldwide and causing serious socio-economic problems. Appropriate
experimental models are essential tools for understanding the pathogenesis, complications,
and genetic or environmental influences that increase the risks of type 2 diabetes and
testing of various therapeutic agents. The animal models of type 2 diabetes can be obtained
either spontaneously or induced by chemicals or dietary or surgical manipulations and/or by …