Dysfunction of photoreceptors, retinal pigment epithelium (RPE) or both contribute to the
initiation and progression of several outer retinal disorders. Disrupted Müller glia function
might additionally subsidize to these diseases. Mitochondrial malfunctioning is importantly
associated with outer retina pathologies, which can be classified as primary and secondary
mitochondrial disorders. This review highlights the importance of oxidative stress and
mitochondrial DNA damage, underlying outer retinal disorders. Indeed, the metabolically …