Immunohistochemical analysis of L1 cell adhesion molecule and high endothelial venules in breast cancer brain metastasis
G Karpathiou, F Camy, JM Dumollard… - Pathology-Research and …, 2021 - Elsevier
Background The vasculature is a crucial factor in tumor development. Vascular co-option
achieved by the L1 cell adhesion molecule (L1CAM) and lymphocyte recruitment inside
tumors by high endothelial venules (HEVs) are important prognostic factors in primary breast
cancer. Their status in breast cancer brain metastasis is unknown. Aim of the study To
explore the status of L1CAMs and HEVs in this tumor compartment. Material and methods
Thirty resected breast cancer brain metastases were immunohistochemically studied for …
achieved by the L1 cell adhesion molecule (L1CAM) and lymphocyte recruitment inside
tumors by high endothelial venules (HEVs) are important prognostic factors in primary breast
cancer. Their status in breast cancer brain metastasis is unknown. Aim of the study To
explore the status of L1CAMs and HEVs in this tumor compartment. Material and methods
Thirty resected breast cancer brain metastases were immunohistochemically studied for …
