A multinational survey of prevalence and patterns of laxative use among adults with self‐defined constipation

A Wald, C Scarpignato… - Alimentary …, 2008 - Wiley Online Library
A Wald, C Scarpignato, S Mueller‐Lissner, MA Kamm, U Hinkel, I Helfrich, C Schuijt…
Alimentary pharmacology & therapeutics, 2008Wiley Online Library
Background While numerous studies report prevalence of constipation, use of laxatives is
poorly understood. Aim To conduct a survey in seven countries evaluating prevalence of
constipation and laxative use in its treatment. Methods Thirteen thousand eight hundred
seventy‐nine adults [approximately 2000 each from US, UK, Germany (GE), France (FR),
Italy (IT), Brazil (BR) and South Korea (SK)] completed questionnaires assessing
occurrence, frequency, duration and laxative use for treating constipation. Results Overall …
Summary
Background  While numerous studies report prevalence of constipation, use of laxatives is poorly understood.
Aim  To conduct a survey in seven countries evaluating prevalence of constipation and laxative use in its treatment.
Methods  Thirteen thousand eight hundred seventy‐nine adults [approximately 2000 each from US, UK, Germany (GE), France (FR), Italy (IT), Brazil (BR) and South Korea (SK)] completed questionnaires assessing occurrence, frequency, duration and laxative use for treating constipation.
Results  Overall, 12.3% of adults had constipation [range: 5% (GE) to 18% (US)] in the prior year. A greater percent of women from all countries and elderly from all except SK and BR reported constipation; odds ratios for constipation among women and elderly were 2.43 (95% CI: 2.18–2.71) and 1.5 (95% CI: 1.25–1.73) vs. men and young subjects. Among those with constipation, 16% (SK) to 40% (US) used laxatives. Laxative use was generally associated with increasing age, symptom frequency and lower income and education. A similar percentage of men and women with constipation reported using laxatives; a greater percentage of women used laxatives for a longer time.
Conclusions  Prevalence of self‐defined constipation and laxative use varies among countries. Prevalence is generally related to gender and age, whereas laxative use is related to age, but not to gender.
Wiley Online Library