[HTML][HTML] FbsC, a novel fibrinogen-binding protein, promotes Streptococcus agalactiae-host cell interactions
M Buscetta, S Papasergi, A Firon, G Pietrocola… - Journal of Biological …, 2014 - ASBMB
Streptococcus agalactiae (group B Streptococcus or GBS) is a common cause of invasive
infections in newborn infants and adults. The ability of GBS to bind human fibrinogen is of
crucial importance in promoting colonization and invasion of host barriers. We characterized
here a novel fibrinogen-binding protein of GBS, designated FbsC (Gbs0791), which is
encoded by the prototype GBS strain NEM316. FbsC, which bears two bacterial
immunoglobulin-like tandem repeat domains and a C-terminal cell wall-anchoring motif …
infections in newborn infants and adults. The ability of GBS to bind human fibrinogen is of
crucial importance in promoting colonization and invasion of host barriers. We characterized
here a novel fibrinogen-binding protein of GBS, designated FbsC (Gbs0791), which is
encoded by the prototype GBS strain NEM316. FbsC, which bears two bacterial
immunoglobulin-like tandem repeat domains and a C-terminal cell wall-anchoring motif …