Markers for human brain pericytes and smooth muscle cells

LCD Smyth, J Rustenhoven, EL Scotter… - Journal of chemical …, 2018 - Elsevier
Brain pericytes and vascular smooth muscle cells (vSMCs) are a critical component of the
neurovascular unit and are important in regulating cerebral blood flow and blood-brain
barrier integrity. Identification of subtypes of mural cells in tissue and in vitro is important to
any study of their function, therefore we identified distinct mural cell morphologies in
neurologically normal post-mortem human brain. Further, the distribution of mural cell
markers platelet-derived growth factor receptor-β (PDGFRβ), α-smooth muscle actin (αSMA) …