Early growth characteristics and the risk of reduced lung function and asthma: a meta-analysis of 25,000 children

HT Den Dekker… - Journal of allergy and …, 2016 - Elsevier
Background Children born preterm or with a small size for gestational age are at increased
risk for childhood asthma. Objective We sought to assess the hypothesis that these
associations are explained by reduced airway patency. Methods We used individual
participant data of 24,938 children from 24 birth cohorts to examine and meta-analyze the
associations of gestational age, size for gestational age, and infant weight gain with
childhood lung function and asthma (age range, 3.9-19.1 years). Second, we explored …