The metabolic effects of 2-week fructose feeding in normal subjects

PA Crapo, OG Kolterman - The American journal of clinical nutrition, 1984 - Elsevier
We studied the metabolic effects of 2 wk of fructose feeding as the sweetener in the diet of
11 normal individuals. The data demonstrated 1) no adverse effects of the fructose
containing diet on triglyceride, pyruvate, lactate, or uric acid metabolism; 2) no apparent
adaptation in the metabolism of fructose; 3) markedly flattened postprandial serum glucose
and insulin responses to pure fructose; and 4) a modest decline in postprandial glucose and
insulin levels after ingestion of standard fructose containing mixed meals as compared to …