Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects

H Beck-Nielsen, O Pedersen, HO Lindskov - The American journal of …, 1980 - Elsevier
We have studied whether the sucrose-induced reduction of insulin sensitivity and cellular
insulin binding in normal man is related to the fructose or the glucose moiety. Seven young
healthy subjects were fed their usual diets plus 1000 kcal extra glucose per day and eight
young healthy subjects were fed their usual diets with addition of 1000 kcal extra fructose
per day. The dietary regimens continued for 1 week. Before change of diet there were no
statistically significant differences between body weight and fasting plasma concentrations …