Successful bacterial pathogens produce an array of virulence factors that allow subversion of the immune system and persistence within the host. For example, uropathogenic
Anna Waldhuber, Manoj Puthia, Andreas Wieser, Christine Cirl, Susanne Dürr, Silke Neumann-Pfeifer, Simone Albrecht, Franziska Römmler, Tina Müller, Yunji Zheng, Sören Schubert, Olaf Groß, Catharina Svanborg, Thomas Miethke
CFT073 induced the expression of the NLRP3 inflammasome in vivo and triggered IL-1β secretion via this inflammasome.